What is Sporanox?

Sporanox is an antifungal medication used to treat serious fungal infections. It works by killing sensitive fungi by interfering with the formation of the fungal cell membrane. Sporanox is used to treat infections caused by fungus, which can invade any part of the body including the lungs, mouth or throat, toenails, or fingernails. Sporanox may also be used for purposes not listed in this medication guide.


Health Benefits of Sporanox

Some potential benefits associated with using Sporanox include:

– Reducing or eliminating fungal infections

– Treating toenail or fingernail fungus

– Reducing symptoms associated with fungal infections such as itching, redness, and swelling

Side Effects of Sporanox

Side effects associated with using Sporanox can include:

– Nausea

– Diarrhea

– Stomach pain

– Headache

– Dizziness

– Rash

Sporanox is available in the form of a capsule, and it is typically taken two or three times a day. It should be taken with food. Some common side effects associated with taking Sporanox include nausea, diarrhea, stomach pain, headache, dizziness, and rash. These side effects are usually mild and resolve on their own. If you experience any severe side effects, consult your doctor immediately.

Dosage and Administration of Sporanox

Sporanox is available in oral capsule and solution form. The usual dose for adults is 100 mg (two 50 mg capsules) once daily. For children, the dose is based on weight.

The capsules should be taken with food, and the solution can be taken with or without food.

To treat toenail or fingernail fungus, the recommended dose is 200 mg (four 50 mg capsules) once daily for 12 weeks.

To prevent reinfection, it is important to keep your nails clean and trim, and to avoid contact with people who have infections using this medication.


Sporanox can interact with other medications, vitamins, or herbs you may be taking. An interaction is when a substance changes the way a drug works. This can be harmful or prevent the drug from working well.

To help avoid interactions, your doctor should manage all of your medications carefully. Be sure to tell your doctor about all medications, vitamins, or herbs you’re taking. To find out how this drug might interact with something else you’re taking, talk to your doctor or pharmacist.

Examples of drugs that can cause interactions with Sporanox are:

– Ketoconazole

– Itraconazole

– Erythromycin

– Rifampin

– St. John’s wort

– Cyclosporine

This is not a complete list of drugs that may interact with Sporanox. Taking drug interactions into account, Sporanox should be used with caution in patients who are taking ketoconazole, itraconazole, or other medications for fungal infections. In addition, patients taking rifampin or St. John’s wort should use this medication with caution. Patients who are taking cyclosporine should be monitored closely by their doctor.

Mechanism of Action

The exact mechanism of action of Sporanox is unknown, but it is thought to work by interfering with the formation of the fungal cell membrane. This makes the fungus more sensitive to the effects of other antifungal medications. Sporanox is classified as an azole antifungal medication.

Azole antifungals work by inhibiting the synthesis of ergosterol, which is a vital component of the fungal cell membrane. Inhibiting the synthesis of ergosterol makes the fungal cell membrane more permeable, which leads to cell death.


Sporanox is rapidly absorbed from the gastrointestinal tract and peak plasma concentrations are reached within two to four hours. Sporanox is extensively metabolized in the liver, and the metabolites are excreted in the urine and feces. The half-life of Sporanox ranges from 20 to 50 hours.

Alternatives to Sporanox

There are many alternative antifungal medications available. Some examples include:





Your doctor can help you choose the best medication for your individual needs.