PDR Health


What is Spectracef?

Generic name: Cefditoren

Spectracef (cefuroxime axetil) is a cephalosporin antibiotic. It works by interfering with the bacteria’s cell wall formation, causing it to eventually rupture and die.

Spectracef is used to treat infections caused by bacteria, including upper respiratory infections, ear infections, skin infections, and urinary tract infections.

Spectracef may also be used for purposes not listed in this medication guide.


Health Benefits

Spectracef offers the following health benefits:

Treats bacterial infections

Reduces ear pain and inflammation

Soothes skin irritation

Side Effects

Some common side effects of Spectracef include upset stomach, diarrhea, and headache. More serious side effects may include allergic reactions and kidney problems. Do not take Spectracef if you are allergic to cefuroxime axetil or any other ingredient in the medication. Talk to your doctor about all other medications you are taking before starting treatment with Spectracef to avoid any potentially harmful drug interactions.

Pregnant or nursing mothers should not take Spectracef unless advised to do so by their healthcare provider.

Dosage & Administration

Spectracef is available in tablet and suspension form. The usual adult dose for the tablet form is 250 mg to 500 mg twice daily, depending on the severity of the infection being treated. For the suspension form, the recommended dose is 5 mL to 10 mL (250 mg to 500 mg) twice daily. Treatment should continue for 7 to 14 days or as directed by your healthcare provider.


Drug interactions may occur with Spectracef. To avoid potential drug interactions, you should keep a list of all the medication you are taking and share it with your healthcare provider and pharmacist. Do not start, stop, or change the dosage of any medications without your doctor’s approval.

Mechanism of Action

The mechanism of action of Spectracef is not completely understood. It is thought to work by interfering with the bacteria’s cell wall formation, causing it to eventually rupture and die.


Spectracef is rapidly absorbed following oral administration. Peak concentrations are reached within 1 to 2 hours. The half-life of the medication is approximately 1.5 hours. Spectracef is excreted in the urine and feces.

How long does it take to work?

Spectracef begins to work within 1 to 2 hours after being taken. However, it may take a few days for the full effect of the medication to be seen.

Alternatives to Spectracef

Alternatives to Spectracef include other cephalosporin antibiotics such as cefaclor and cefuroxime. Talk to your healthcare provider about the best option for you.

Is cefaclor more effective than cefuroxime?

There is no definitive answer to this question as both medications are effective against a variety of bacterial infections. However, cefaclor may be more effective against certain types of bacteria. Talk to your healthcare provider about the best option for you.

Long-term effects of Spectracef

There are no known long-term effects of Spectracef. However, as with all medications, there is a potential for side effects. If you experience any serious side effects, stop taking the medication and contact your healthcare provider immediately.