Generic name: Acitretin
What is Soriatane?
Soriatane (acitretin) is a retinoid medication used to treat psoriasis. It works by reducing skin cell production.
Health Benefits
Soriatane is used to treat severe psoriasis that has not responded to other treatments.
This medication may also be used to help relieve the painful symptoms of ichthyosis, a condition that results in dry, scaly skin.
Side Effects
The most common side effects associated with Soriatane are dryness and irritation of the skin, mouth, eyes, and vagina. These effects usually improve with continued use of the medication. Other potential side effects include:
– headache
– dizziness or drowsiness
– hair loss
– joint pain or stiffness
– nausea or vomiting
Soriatane can also cause birth defects. If you are pregnant or planning to become pregnant, you should not take this medication. You should also use effective birth control while taking Soriatane and for at least three years after your last dose.
If you experience any serious side effects, stop taking Soriatane and contact your doctor immediately.
Please consult with a healthcare professional before starting any treatment.
Dosages
The usual starting dose of Soriatane is 25 mg daily. Your doctor will increase your dose gradually, depending on your response to the medication. The maximum recommended dose is 50 mg daily.
Soriatane should be taken with food and a full glass of water. It is important to drink plenty of fluids while taking this medication to prevent kidney stones from forming.
If you miss a dose of Soriatane, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take two doses at once.
Interactions
Soriatane may interact with other medications, including:
– vitamin A supplements
– tetracycline antibiotics
– phenytoin
– warfarin
Before taking Soriatane, be sure to tell your doctor about all other medications you are taking. You should also mention any vitamins, supplements, or herbal remedies you are using.
Do not take Soriatane if you are pregnant or planning to become pregnant. This medication can cause birth defects. You should also use effective birth control while taking Soriatane and for at least three years after your last dose.
Mechanism of Action
Soriatane works by reducing skin cell production. It is a retinoid, which means it is similar to vitamin A. Retinoids are known to help control the growth of skin cells.
Soriatane is thought to work by decreasing the production of certain substances that are involved in the development of psoriasis. These substances include prostaglandins and leukotrienes. Soriatane may also help to reduce inflammation.
Please consult with a healthcare professional before starting any treatment.
Pharmacokinetics
Soriatane is absorbed rapidly after oral administration. The peak concentration in the blood occurs within 2 to 4 hours. Soriatane is widely distributed throughout the body and is bound to plasma proteins.
Soriatane is metabolized in the liver and excreted in the urine. The half-life of Soriatane is about 24 hours.
Pregnancy and Lactation
Soriatane can cause birth defects. If you are pregnant or planning to become pregnant, you should not take this medication. You should also use effective birth control while taking Soriatane and for at least three years after your last dose.
