PDR Health


Generic name: Zaleplon

What is Sonata (Zaleplon)?

Sonata is a prescription medication used to treat insomnia. It belongs to a class of drugs called sedative-hypnotics, which work by slowing down the nervous system.


Health Benefits

Sonata is used to treat insomnia, which is a sleep disorder that can cause difficulty falling asleep or staying asleep. Sonata may help people with insomnia fall asleep faster and sleep through the night.

In addition to its use as a treatment for insomnia, Sonata has also been shown to be effective in treating some other conditions, including:

– Anxiety

– Depression

– Fibromyalgia

– Chronic pain syndromes like migraines and tension headaches

Side Effects

The most common side effects of Sonata include:

– Drowsiness during the day


– Headache

– Nausea

– Diarrhea

– Dry mouth

Less common side effects include:

– Memory problems

– Sleepwalking

– Depression

– Anxiety

– Hallucinations

As with any medication, there is always the potential for side effects. Be sure to talk to your doctor about the risks and benefits of taking Sonata before starting treatment.

Dosage and Administration

Sonata is available in 5 mg, 10 mg, and 20 mg capsules. The usual dose for adults is 10 mg taken once daily at bedtime. For seniors or people with liver disease, the starting dose is 5 mg once daily at bedtime. Sonata should be taken on an empty stomach, at least 30 minutes before bedtime.

If you miss a dose of Sonata, take it as soon as you remember. If it is close to the time of your next dose, skip the missed dose and continue on your regular schedule. Do not take two doses of Sonata at the same time.


Sonata may interact with other medications, including:

– Alcohol

– Antidepressants

– Anti-anxiety medications

– Anticonvulsants

– Muscle relaxants

It is important to speak with your doctor about all of the medications you are taking, including over-the-counter drugs, before starting treatment with Sonata.

Mechanism of Action

Sonata works by binding to a specific site in the brain called the omega-1 receptor. This action slows down the activity of the central nervous system, which leads to drowsiness and sleep.


Sonata is rapidly absorbed from the gastrointestinal tract and reaches peak concentrations in the blood within 1 hour. The half-life of Sonata is 1-2 hours, which means it stays in the body for a relatively short time.

Special Populations

Sonata should be used with caution in people with liver disease, as they may be more sensitive to the effects of the drug. Sonata should also be used with caution in people with depression or anxiety, as it may worsen these conditions.

Pregnancy and breastfeeding

Sonata should not be used during pregnancy unless the potential benefits outweigh the potential risks. If you are pregnant or planning to become pregnant, speak with your doctor before taking this medication.

It is not known if Sonata is excreted in breast milk. If you are breastfeeding, speak with your doctor before taking this medication.