What is Relpax?

Relpax (eletriptan) is a headache medicine that narrows blood vessels around the brain. Eletriptan also reduces substances in the body that can trigger headache pain, nausea, sensitivity to light and sound, and other migraine symptoms.

Relpax is used to treat migraines with or without aura in adults.

Relpax

Health Benefits

Relpax can help to relieve the pain of migraines and other types of headaches. It can also help to reduce the symptoms of migraines, such as nausea, sensitivity to light and sound, and other migraine symptoms.

Side Effects

The most common side effects of Relpax include:

Dizziness

Nausea

Tingling or warmth sensation

Muscle weakness

Less common side effects include:

Chest pain or tightness

Shortness of breath

Pounding heartbeats or fluttering in your chest

If you experience any of these side effects, contact your doctor immediately.

Rare side effects include:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, throat, or tongue); strange thoughts or behaviors. If you experience any of these rare side effects, contact your doctor immediately.

Relpax may also cause other side effects. Contact your doctor if you experience any unusual or bothersome side effect.

Dosage

The recommended dose of Relpax is 40 mg taken at the first sign of a migraine headache. If your migraine headache improves after you take eletriptan but returns or worsens after a while, you may take a second dose 2 hours after the first dose. Do not take more than 80 mg in 24 hours.

Interactions

Relpax may interact with other medications. Tell your doctor all prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

Mechanism of Action

The exact mechanism of action of Relpax is unknown. It is thought to work by narrowing blood vessels around the brain and by reducing substances in the body that can trigger headache pain, nausea, sensitivity to light and sound, and other migraine symptoms.

Relpax may be use as preventive therapy for migraines when taken on a regular basis. Ask your doctor if this is an option for you.

Pharmacokinetics

Absorption: Eletriptan is rapidly and completely absorbed following oral administration, with peak plasma concentrations reached in approximately 2 hours.

Distribution: The mean apparent volume of distribution of eletriptan is about 21 L/kg. Plasma protein binding is about 55%.

Metabolism and Excretion: Eletriptan is extensively metabolized by monoamine oxidase (MAO) enzymes, both type A and type B. The primary metabolites are the indole acetic acid derivative and the N-desmethyl metabolite, which have no agonist activity at 5-HT1B/1D receptors. These metabolites are not pharmacologically active and do not contribute to the pharmacologic effect of eletriptan. Eletriptan and its metabolites are eliminated primarily by hepatic metabolism with minimal renal excretion. The mean elimination half-life is about 5 hours.

Alternatives to Relpax

There are many alternative medications available to treat migraines and other types of headaches. Some of these alternatives include:

Ibuprofen

Aspirin

Tylenol

Excedrin Migraine

Caffeine

Naproxen

Sumatriptan

Rizatriptan

Topiramate

If you experience side effects from Relpax, or if the medication does not relieve your migraine pain, talk to your doctor about other options. There are many effective treatments available and your doctor can help you find the one that is best for you.

Is Aspirin more effective than Relpax?

There is no definitive answer to this question as each person responds to medications differently. Some people find that aspirin is more effective for their migraines, while others find that Relpax works better for them. If you are experiencing side effects from Relpax, or if the medication is not relieving your migraine pain, talk to your doctor about other options. There are many effective treatments available and your doctor can help you find the one that is best for you.