PDR Health


What is propine?

Propine is an organic compound with the chemical formula C3H5N. It is a clear, colorless liquid with a sweet, ammonia-like odor. Propine is used as a solvent and as a reagent in organic synthesis.

Propine is produced by the reduction of propionic acid. Industrially, this process typically uses sodium hypochlorite as the reducing agent. This reaction produces chlorine gas, which must be handled carefully.


Health Benefits of Propine

Although propine is not an essential nutrient, it does have some potential health benefits.

Propine has been shown to act as an anticonvulsant in animal studies. This means that it may help to prevent seizures.

In addition, propine has been shown to reduce inflammation and pain in rats. This suggests that it may be beneficial for treating conditions like arthritis and inflammatory bowel disease.

Finally, propine has been shown to kill cancer cells in test-tube studies. However, more research is needed to determine whether or not it can effectively treat cancer in humans.

Side Effects of Propine

Propine is generally considered to be safe when used in small amounts. However, it can cause some side effects when taken in large doses.

The most common side effect of propine is nausea. Other potential side effects include vomiting, dizziness, and drowsiness.

Propine can also be toxic if taken in large amounts. Symptoms of propine toxicity include seizures, coma, and death.

It is important to note that propine is a flammable liquid. It should be stored in a cool, dry place away from heat or open flames.


There is no Recommended Dietary Allowance (RDA) for propine. However, the safe upper limit for propine intake is 0.15 grams per day.

Propine is typically taken in capsule form. The usual dose is 0.05-0.1 grams, three times per day.


Propine may interact with certain medications. Therefore, it is important to talk to your doctor before taking propine if you are taking any other drugs.

Propine may also interact with alcohol. Drinking alcohol while taking propine can increase the risk of side effects.

Pregnant and breastfeeding women should avoid propine. There is not enough research to determine whether or not it is safe for them to take.

Mechanism of Action

The exact mechanism of action of propine is not known. However, it is thought to work by modulating the activity of GABA, a neurotransmitter that plays a role in seizures.

In addition, propine may help to reduce inflammation by inhibiting the production of inflammatory cytokines.

Propine also has antioxidant and anticancer properties. These effects are thought to be mediated by its ability to scavenge free radicals and inhibit cell proliferation.


Propine is rapidly absorbed from the gastrointestinal tract. It is metabolized in the liver and excreted in the urine.

The half-life of propine is 1-2 hours. This means that it takes about 1-2 hours for the body to eliminate half of the propine that has been consumed.

Alternatives to Propine

If you are looking for an alternative to propine, there are several other options available.

magnesium sulfate, gabapentin, and pregabalin are all anticonvulsants that may be effective in preventing seizures.

There are also many anti-inflammatory drugs that can help to reduce pain and inflammation. These include aspirin, ibuprofen, and naproxen.

Finally, there are a variety of anticancer agents that can kill cancer cells. These include chemotherapy drugs, radiation therapy, and surgery.

Propine is a potentially useful compound with a variety of health benefits. However, more research is needed to determine its safety and effectiveness. If you are considering taking propine, be sure to talk to your doctor first.

How long does it take to work?

The effects of propine are typically felt within 30 minutes to 1 hour. The full effects may not be evident for 2-3 hours.

How long does it last?

The effects of propine typically last for 4-6 hours. However, some people may experience residual effects for up to 24 hours.