PDR Health


Generic name: Butoconazole nitrate

What is Mycelex-3?

Mycelex-3 is an antifungal medicine. It fights infections caused by fungi.

Mycelex-3 is used to treat vaginal yeast infections.

Health Benefits of Mycelex-3

Vaginal yeast infections are a common problem in women. They can cause itching, burning, and redness of the vagina and vulva. Vaginal yeast infections are usually treated with antifungal medicines that are taken by mouth or inserted into the vagina as creams or suppositories.

Side Effects of Mycelex-3

The most common side effects of Mycelex-3 include:



Stomach upset

These are the most common side effects of Mycelex-3. Talk to your doctor if you have any side effect that bothers you or does not go away.

Dosages of Mycelex-3

The usual dose of Mycelex-3 for vaginal yeast infection is:

One tablet taken by mouth three times a day for 7 days

If you have any questions about doses, talk to your doctor or pharmacist. They can help you figure out the best dose for you.

Interactions of Mycelex-3

Mycelex-3 can interact with other medications, vitamins, or herbs you may be taking. An interaction is when a substance changes the way a drug works. This can be harmful or prevent the drug from working well.

To help avoid interactions, your doctor should manage all of your medications carefully. Be sure to tell your doctor about all medications, vitamins, or herbs you’re taking. To find out how this drug might interact with something else you’re taking, talk to your doctor or pharmacist.

Examples of drugs that can cause interactions with Mycelex-3 include:


macrolide antibiotics



This is not a complete list of drugs that may interact with Mycelex-3. Taking this medicine with any of these drugs can cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If these medicines are used together, your doctor will watch for side effects.

Mechanism of Action of Mycelex-3

Mycelex-3 belongs to a class of drugs called azole antifungals. A class of drugs is a group of medications that work in a similar way. These drugs are often used to treat similar conditions.

Mycelex-3 works by killing fungi or preventing their growth. It does this by stopping the fungi from making a substance called ergosterol. Ergosterol is a vital part of the fungal cell membrane. Without it, the cells burst and the fungi die.

Pharmacokinetics of Mycelex-3

Mycelex-3 is well absorbed from the gastrointestinal tract. Peak plasma concentrations occur 2 to 3 hours after oral administration. The elimination half-life of Mycelex-3 is 8 to 10 hours.

Mycelex-3 is widely distributed in body tissues and fluids. Plasma protein binding is low (less than 10%). Mycelex-3 is metabolized in the liver and excreted mainly in the urine as metabolites. Less than 1% of an oral dose is excreted unchanged in the urine.

Alternatives to Mycelex-3

Other drugs are available that can treat vaginal yeast infections. Some may be better suited for you than others. Talk to your doctor about other drug options that may work for you.

Examples of other drugs that may be used to treat vaginal yeast infections include:

clotrimazole (Gyne-Lotrimin, Mycelex)

fluconazole (Diflucan)

miconazole (Monistat)

tioconazole (Vagisil)

If you have any questions about alternatives to Mycelex-3, talk with your doctor.

Symptoms of an Overdose

If you think you’ve taken too much of this drug, call your doctor. You may need medical treatment if you experience any of the following symptoms:

stomach pain

nausea and vomiting




If you have any questions about how much of this drug is safe to take, talk with your doctor or pharmacist.