Description

Mirapex (pramipexole) is a dopamine agonist that works by restoring the balance of dopamine in the brain. Mirapex is used to treat Parkinson’s disease. Mirapex may also be used for purposes not listed in this medication guide. You should not use Mirapex if you are allergic to it, or if:

You should not use Mirapex if you are allergic to it, or if:

– you have uncontrolled high blood pressure;

– you have severe heart disease or recent heart attack;

– you are taking certain other medicines (such as ketoconazole, nefazodone, ritonavir, or telithromycin).

To make sure Mirapex is safe for you, tell your doctor if you have ever had:

– heart disease, congestive heart failure;

– a stroke or “mini-stroke”;

– low blood pressure;

– depression, anxiety, or other mental illness;

Side Effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

– a light-headed feeling, like you might pass out;

– fast or pounding heartbeats and sudden dizziness (like you might pass out);

– swelling in your hands, ankles, or feet;

– feeling short of breath;

– confusion, hallucinations; or

– uncontrolled muscle movements in your face (chewing, lip smacking, frowning, tongue movement, blinking or eye movement).

Dosages

Usual Adult Dose for Parkinson’s Disease

Initial Dose: Mirapex should be initiated at a dose of 0.125 mg orally once daily, at bedtime. The dosage may be increased by 0.125 mg to 0.25 mg after one week if needed.

Maintenance Dose: After an adequate response is achieved, the dosage of Mirapex should be increased gradually in increments of 0.125 mg to 0.25 mg every one to two weeks until the optimum dosage is reached or side effects become bothersome. The usual effective dose range is 1.5 mg/day to 4.5 mg/day given in divided doses (two or three times daily).

Maximum Dose: The maximum recommended dose is 4.5 mg/day.

Comments: -The Mirapex dosage should be increased gradually until the desired clinical effect is achieved or side effects become bothersome, at which time the Mirapex dosage should be decreased slightly.

-If a patient experiences bothersome day-time drowsiness or vivid dreams at the current Mirapex dosage, the dose should be reduced.

-If a patient develops daytime sleepiness or falls asleep during activities that require active participation (e.g., conversations, eating, etc.), Mirapex should be discontinued.

Uses: -Treatment of signs and symptoms of idiopathic Parkinson’s disease.

Mirapex (pramipexole) is a dopamine agonist that works by restoring the balance of dopamine in the brain. Mirapex is used to treat Parkinson’s disease. Mirapex may also be used for purposes not listed in this medication guide.