What is Lorabid?

Lorabid is a prescription medication used to treat various types of bacterial infections. It belongs to a class of drugs called quinolone antibiotics. Lorabid works by killing bacteria or preventing their growth.

Lorabid is available in oral tablet and suspension form.

Lorabid

Health Benefits

Lorabid is used to treat various types of bacterial infections. These include:

Ear infections

Skin infections

Urinary tract infection

Kidney infection

Pelvic inflammatory disease

Bacterial diarrhea

Inhalation anthrax (post-exposure)

Side Effects & Precautions

Common side effects of Lorabid include nausea, vomiting, diarrhea, and headache. Lorabid may also cause dizziness. Do not drive or operate heavy machinery until you know how Lorabid affects you.

Lorabid should not be used by people with a history of hypersensitivity to quinolones or other antibiotics. It should also be used with caution in people with a history of epilepsy or a seizure disorder.

Pregnant or breastfeeding women should not take Lorabid.

Dosages

The usual adult dose of Lorabid for most infections is 250 mg every 12 hours. The maximum dose is 4 grams per day.

For the treatment of inhalation anthrax, the recommended dose is 500 mg every 12 hours for 60 days.

Interactions

Lorabid may interact with other medications. Tell your doctor all prescription and over-the-counter medications and supplements you take.

Examples of medications that may interact with Lorabid include:

Antacids

Iron supplements

Probenecid

Warfarin

Theophylline

This is not a complete list of Lorabid drug interactions. Ask your doctor or pharmacist for more information.

Mechanism of Action

Lorabid belongs to a class of drugs called quinolone antibiotics. It works by binding to DNA and preventing bacteria from replicating. This action kills the bacteria or prevents their growth.

Pharmacokinetics

Lorabid is rapidly absorbed from the gastrointestinal tract. The oral bioavailability is about 100%.

The half-life of Lorabid is 3-4 hours.

Lorabid is eliminated primarily by the kidneys.

Clinical Trials

In clinical trials, Lorabid was effective in the treatment of various types of bacterial infections.

The most common side effects reported in clinical trials include nausea, vomiting, diarrhea, and headache.

Alternatives to Lorabid

Alternatives to Lorabid include other quinolone antibiotics such as ciprofloxacin, levofloxacin, and ofloxacin.

Lorabid may not be the best treatment option for you if you have certain medical conditions. Be sure to tell your doctor about all your medical conditions before taking this medication.

Chemistry

Lorabid (INN) is the international nonproprietary name for the antibiotic drug lomefloxacin, which is a fluoroquinolone.

It is a white to yellowish-white powder that is insoluble in water.

The empirical formula for lomefloxacin is C18H17FN2O4 and the molecular weight is 350.33 g/mol.

Symptoms of an Overdose

There is no specific antidote for a lomefloxacin overdose. Treatment is supportive and symptomatic.

In case of an overdose, call your local poison control center at 1-800-222-1222. If the person has collapsed or is not breathing, call 911.

Storage

Lorabid should be stored at room temperature, 20°C to 25°C (68°F to 77°F).

Do not freeze Lorabid oral suspension. Shake well before using.

History

Lorabid was first approved by the FDA in 1993.

It is manufactured by Pfizer under the brand name Maxaquin.

Generic Name: lomefloxacin (loe me FLOX a sin)

Brand Names: Maxaquin, Lorabid

Is ciprofloxacin more effective than lomefloxacin?

There is no definitive answer to this question as both antibiotics are effective against a variety of bacterial infections. Some studies suggest that ciprofloxacin may be more effective than lomefloxacin, while other studies have found no difference in efficacy between the two drugs. Ultimately, the decision of which antibiotic to use should be made on a case-by-case basis by a doctor or other healthcare professional.

How is it supplied

Lorabid is supplied as an immediate-release tablet and an oral suspension.

The tablet is available in two strengths: 250 mg and 500 mg.

The oral suspension is available in one strength: 100 mg/5 mL.

Dosage Forms and Strengths

Tablet, oral:

250 mg

500 mg

Oral suspension, oral:

100 mg/5 mL (30 mL)

Lorabid drug interactions can occur when it is taken with certain other medications. These include antacids, iron supplements, probenecid, warfar