Cephulac, Chronulac, Constilac, Constipol, Correctol 10,Constulose, Duphalac Oral Solution, Enulose Oral Solution, Evalose Oral Solution, Generlac Oral Solution, Kristalose Oral Solution Medication
Lactulose is a type of sugar that is normally broken down and absorbed by the body. However, in some people with liver disease, lactulose cannot be properly metabolized. This can lead to high levels of lactulose in the blood, which can cause serious health problems.
Lactulose is often used as a treatment for constipation and other digestive problems. It is also sometimes used as a laxative.
Lactulose should not be used if you have certain medical conditions, such as kidney disease, diabetes, or an intestinal blockage. Be sure to tell your doctor about all of your medical conditions before taking this medication.
There are potential side effects associated with taking lactulose. These include abdominal pain, bloating, diarrhea, gas, and nausea. If you experience any of these side effects, stop taking lactulose and call your doctor immediately.
Lactulose is a safe and effective medication when used as directed. Be sure to follow all instructions provided by your doctor when taking this medication.
Lactulose is metabolized in the colon by bacteria to short-chain fatty acids (SCFAs), which are then absorbed. Approximately 95% of an oral dose is excreted in the feces as SCFAs within 72 hours, and only 1% is excreted in the urine.
The time to peak plasma concentration (Tmax) of lactulose ranges from 0.5 to 2 hours.
INDICATIONS AND USAGE
Lactulose is indicated for the treatment of constipation and for the prevention of hepatic encephalopathy.
DOSAGE AND ADMINISTRATION
For constipation, the recommended initial dose is 15 to 30 mL orally once daily, adjusted as needed to produce 2 or more soft stools per day.
For hepatic encephalopathy, the recommended initial dose is 15 to 30 mL orally 3 times daily, adjusted as needed to produce 2 or more soft stools per day.
The maximum recommended daily dose of lactulose is 60 mL/day.
HOW TO USE
Lactulose should be taken orally with or without food. Shake the bottle well before each use.
Measure the medication using the provided measuring cup, spoon, or dropper. Do not use a household spoon because it may not give the correct amount.
Take this medication exactly as prescribed by your doctor. Do not take it in larger or smaller amounts or for longer than recommended.
Your doctor may start you on a low dose of lactulose and gradually increase your dose. Follow your doctor’s instructions carefully.
Do not take more than the recommended amount of this medication in a 24-hour period. This can lead to serious side effects.
Take this medication for the entire length of time prescribed by your doctor. Your symptoms may improve before the condition is completely treated.
To prevent constipation, continue taking this medication even if you feel well. Do not stop taking lactulose without talking to your doctor.
To treat hepatic encephalopathy, it is important to take this medication exactly as prescribed by your doctor. Lactulose can help lower ammonia levels in the blood, but it will not cure this condition.
You may need to take lactulose for several days before you notice an improvement in your symptoms. Continue taking this medication even if you feel well. Do not stop taking lactulose without talking to your doctor.
If you are using lactulose for hepatic encephalopathy, your doctor will probably want you to have regular laboratory tests and medical checkups. Be sure to keep all appointments.
This section contains uses of this drug that are not listed in the approved professional labeling for the drug but that may be prescribed by your health care professional. Use this drug for a condition that is listed in this section only if it has been so prescribed by your health care professional. This medication may also be used before certain medical procedures (e.g., sigmoidoscopy, barium enema) to clean the bowel by causing watery stools. It may also be used to decrease high ammonia levels in the blood (hepatic encephalopathy).
Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.
Do not freeze. Do not use lactulose that has been frozen.
Throw away any unused lactulose when it expires. Expired medication can be harmful.