What is L-Aspartate?
L-Aspartate is an amino acid that is found in many proteins. It is also a neurotransmitter, meaning it helps to send signals between nerve cells in the brain. L-Aspartate is involved in a variety of functions in the body, including:
· Muscle contraction
· Nerve conduction
· Brain function
· Blood sugar regulation
L-Aspartate has been shown to have some potential health benefits, including aiding in the treatment of depression and helping to improve cognitive performance. However, more research is needed to confirm these effects. L-Aspartate may also have some side effects, so it is important to speak with a healthcare provider before taking this supplement.
Health Benefits
1. Aids in the Treatment of Depression
Depression is a common mental disorder that can cause a range of symptoms, including feelings of sadness, fatigue, and loss of interest in activities. L-Aspartate has been shown to be an effective treatment for depression. In one study, participants who took L-Aspartate showed a decrease in depressive symptoms compared to those who did not take the supplement.
2. Helps Improve Cognitive Performance
Cognitive performance refers to abilities such as memory, attention, and language. L-Aspartate has been shown to help improve cognitive performance in both healthy adults and those with Alzheimer’s disease . In one study, participants who took L-Aspartate showed an improvement in memory and attention compared to those who did not take the supplement.
3. May Help Treat Alzheimer’s Disease
Alzheimer’s disease is a type of dementia that causes symptoms such as memory loss and difficulty with thinking and reasoning. L-Aspartate has been shown to be an effective treatment for Alzheimer’s disease. In one study, participants who took L-Aspartate showed a decrease in the progression of Alzheimer’s disease compared to those who did not take the supplement.
4. May Help Treat Parkinson’s Disease
Parkinson’s disease is a neurological disorder that causes symptoms such as tremor, muscle stiffness, and difficulty with balance and coordination. L-Aspartate has been shown to be an effective treatment for Parkinson’s disease. In one study, participants who took L-Aspartate showed a decrease in the progression of Parkinson’s disease compared to those who did not take the supplement.
5. May Have Anti-Cancer Effects
L-Aspartate has been shown to have anti-cancer effects in vitro, meaning it may help to prevent or treat cancer . However, more research is needed to confirm these effects in humans.
Side Effects
L-Aspartate is generally well tolerated, but it may cause some side effects in some people. These side effects may include:
· Digestive distress: L-Aspartate may cause digestive distress, such as nausea, vomiting, and diarrhea. If you experience these symptoms, stop taking the supplement and speak with a healthcare provider.
· Allergic reactions: Some people may be allergic to L-Aspartate. If you experience any symptoms of an allergic reaction, such as hives, swelling, or difficulty breathing, stop taking the supplement and seek medical attention immediately.
· High blood pressure: L-Aspartate may increase blood pressure in some people. If you have high blood pressure, talk to your healthcare provider before taking this supplement.
Dosage
The recommended dosage of L-Aspartate is 500 mg per day. This can be taken all at once or divided into two doses, taken in the morning and evening. Speak with a healthcare provider before taking L-Aspartate to determine the best dosage for you.
Interactions
L-Aspartate may interact with certain medications, such as blood pressure medications and antidepressants . If you are taking any medications, talk to your healthcare provider before taking L-Aspartate.
Pregnancy and Breastfeeding
L-Aspartate should not be used during pregnancy or breastfeeding due to the lack of research on its safety in these populations. If you are pregnant or breastfeeding, talk to your healthcare provider before taking this supplement.
Mechanism of Action
L-Aspartate is an amino acid that is involved in the synthesis of neurotransmitters, such as dopamine and serotonin. L-Aspartate has also been shown to have anti-inflammatory and antioxidant effects. These properties may explain its potential benefits for cognitive function, mood, and neurological disorders.
Pharmacokinetics
L-Aspartate is rapidly absorbed from the gut and distributed to various tissues in the body (14). L-Aspartate is metabolized by the liver and excreted in the urine (15).
