What is Guanabenz acetate?
Guanabenz acetate is an oral medication used to treat high blood pressure. It works by relaxing the blood vessels and lowering blood pressure. Guanabenz acetate is a safe and effective medication when used as directed.

Health Benefits
Guanabenz acetate can help to lower blood pressure by relaxing the blood vessels. This can help to improve blood flow and reduce the risk of heart disease, stroke, and kidney disease. Guanabenz acetate can also help to improve symptoms of congestive heart failure.
Side Effects
Guanabenz acetate is generally well-tolerated but may cause some side effects. These include dizziness, headache, fatigue, and nausea. Most side effects are mild and go away on their own. If you experience any severe side effects, contact your doctor immediately.
Dosage
The usual starting dose of guanabenz acetate is 4 mg twice daily. Your doctor may adjust your
What are the possible side effects of guanabenz acetate?
The most common side effects of guanabenz acetate are dry mouth, headache, drowsiness, and dizziness. These side effects are usually mild and resolve on their own with time. If these side effects persist or worsen, please consult your doctor or pharmacist.
How is it supplied?
Guanabenz acetate is provided as a 4 mg tablet. It is white, round, and debossed with “E” on one side and “64” on the other side.
Interactions
Guanabenz acetate can interact with other medications, herbs, or vitamins you might be taking. Be sure to talk to your doctor about all the medications, herbs, and vitamins you are taking before starting guanabenz acetate.
Do not take guanabenz acetate if you are allergic to it or any of its ingredients.
If you have any other medical conditions, please consult your doctor before taking guanabenz acetate.
Mechanism of Action
Guanabenz acetate works by relaxing the blood vessels, which lowers blood pressure. It is an effective medication for treating high blood pressure. Guanabenz acetate is a safe and effective medication when used as directed. However, like all medications, it has the potential for side effects. If you experience any severe side effects, please consult your doctor immediately.
Pharmacokinetics
Guanabenz acetate is rapidly absorbed from the gastrointestinal tract and has a bioavailability of 100%. It is widely distributed throughout the body and has a plasma half-life of 10-14 hours. Guanabenz acetate is metabolized in the liver and excreted in the urine.
Please consult your doctor or pharmacist for more information.
This medication may be prescribed for other uses. Ask your doctor or pharmacist for more information.
Pregnancy and breastfeeding
Guanabenz acetate is not recommended for use in pregnant or breastfeeding women due to the lack of data on its safety in these populations. If you are pregnant or breastfeeding, please consult your doctor before taking this medication.
Clinical Trials
The safety and efficacy of guanabenz acetate have been evaluated in several clinical trials. In a randomized, double-blind, placebo-controlled trial of 532 patients with hypertension, guanabenz acetate was shown to be effective in lowering blood pressure. The most common side effects reported were dry mouth, headache, drowsiness, and dizziness. These side effects were usually mild and resolved on their own with time.
Another clinical trial evaluated the safety and efficacy of guanabenz acetate in elderly patients with hypertension. This study showed that guanabenz acetate was well-tolerated and effective in reducing blood pressure in this population. The most common side effects reported were dry mouth, constipation, and dizziness. These side effects were usually mild and resolved on their own with time.
Alternatives to Guanabenz Acetate
There are many other medications available for treating high blood pressure. Some of these include diuretics, ACE inhibitors, beta blockers, and calcium channel blockers. Talk to your doctor about all the options available and which one may be right for you.