What is fluorometholone?

Fluorometholone is a steroid medicine. It prevents the release of substances in the body that cause inflammation.

Fluorometholone topical (for the skin) is used to treat the swelling, redness, itching, and burning of skin conditions such as eczema, psoriasis, dandruff, seborrhea, and tinea versicolor.

Fluorometholone ophthalmic (for the eyes) is used to treat short-term inflammation of the eye due to allergies or other causes.

Fluorometholone may also be used for purposes not listed in this medication guide.

Fluorometholone (FML)

Health Benefits

Fluorometholone has many potential health benefits. Some of these include:

1. Reducing inflammation

2. Treating skin conditions such as eczema, psoriasis, and dandruff

3. Treating eye conditions such as allergies or other causes of inflammation

4. Potentially boosting the immune system

5. Reducing the risk of cancer

Side Effects

Fluorometholone may cause side effects. Some of these include:

1. Stomach upset

2. Nausea

3. Vomiting

4. Diarrhea

5. Dizziness

6. headache

7. Blurred vision


The usual dose of fluorometholone is 0.01% to 0.03% applied to the affected area two or three times daily for no more than two weeks at a time.

For ophthalmic use (eye drops), the usual dose is one or two drops in the affected eye(s) up to four times daily.


Fluorometholone may interact with other drugs. Some of these include:

1. Steroid medications such as prednisone, hydrocortisone, and dexamethasone

2. Immunosuppressant medications such as cyclosporine and tacrolimus

3. Antibiotics such as neomycin, polymyxin B, and bacitracin

4. Diabetes medications such as insulin and metformin

5. Birth control pills and other hormone-based contraceptives

Mechanism of Action

The exact mechanism of action of fluorometholone is unknown. However, it is thought to work by inhibiting the release of inflammatory mediators such as histamine and leukotrienes. Additionally, it may boost the immune system by increasing the production of white blood cells and antibodies.

Pregnancy and Fluorometholone

Fluorometholone is not recommended for use during pregnancy. It may cause harm to a developing fetus. If you are pregnant, talk to your doctor about the risks of using this medication.

It is not known whether fluorometholone passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

What Happens If I Miss A Dose?

Apply the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not use extra medicine to make up the missed dose.



Fluorometholone is poorly absorbed through the skin.


Fluorometholone has a large volume of distribution and is widely distributed throughout the body.


Fluorometholone is metabolized in the liver by the cytochrome P450 enzyme system.


Fluorometholone is eliminated from the body primarily through the kidneys.


Some alternatives to fluorometholone include:

1. Hydrocortisone

2. Prednisone

3. Dexamethasone

4. Cyclosporine

5. Tacrolimus

Is Hydrocortisone more effective than Fluorometholone?

There is no definitive answer to this question. Both hydrocortisone and fluorometholone are effective at reducing inflammation. However, some studies suggest that hydrocortisone may be more effective than fluorometholone in treating certain conditions such as eczema.

What is the difference between Hydrocortisone and Fluorometholone?

The main difference between hydrocortisone and fluorometholone is that hydrocortisone is a synthetic cortisol while fluorometholone is a synthetic glucocorticoid. Additionally, hydrocortisone has a wider range of uses than fluorometholone. Finally, hydrocortisone is available in a cream, ointment, lotion, and tablet form while fluorometholone is only available as an eye drop and ointment.