What is Flexeril?

Flexeril is a muscle relaxant that works by blocking pain signals from the brain to the body. It is used to treat spasticity associated with conditions such as multiple sclerosis, ALS, spinal cord injury, and cerebral palsy.

Flexeril

What are the side effects of Flexeril?

The most common side effects of Flexeril include drowsiness, dizziness, headache, nausea, and vomiting. Less common side effects include constipation, dry mouth, and blurred vision.

Is Flexeril safe for long-term use?

Yes, Flexeril is safe for long-term use. However, you should speak with your doctor if you have any concerns about taking Flexeril for an extended period of time.

Can Flexeril be addictive?

No, Flexeril is not addictive. however, it can cause dependence if it is taken for extended periods of time. If you feel like you may be dependent on Flexeril, speak with your doctor.

Mechanism of action

The exact mechanism of action of Flexeril is not known, but it is thought to work by inhibiting the reuptake of norepinephrine and serotonin in the brain, which leads to increased levels of these neurotransmitters in the body.

Dosage and administration

Flexeril is available as tablets, capsules, or an oral solution. The usual adult dose is 5 mg three times a day. The maximum recommended dose is 20 mg per day.

Pharmacokinetics

Flexeril is rapidly absorbed from the gastrointestinal tract and has a bioavailability of 50%. It is widely distributed throughout the body and has a plasma protein binding of 96%. Flexeril is metabolized in the liver and excreted in the urine.

What should I do if I miss a dose of Flexeril?

If you miss a dose of Flexeril, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue on your regular dosing schedule. Do not take two doses of Flexeril at the same time.

How long does Flexeril stay in your system?

Flexeril has a half-life of 6-12 hours. This means that it will take 6-12 hours for the drug to be reduced by half in your body. Flexeril will stay in your system for 1-2 days after you stop taking it.

Can I drink alcohol while taking Flexeril?

No, you should not drink alcohol while taking Flexeril. Alcohol can increase the effects of Flexeril and lead to increased drowsiness and dizziness.

What should I avoid while taking Flexeril?

You should avoid driving or operating heavy machinery while taking Flexeril, as it can cause drowsiness and dizziness. You should also avoid drinking alcohol while taking Flexeril.

Pregnancy and breastfeeding

Flexeril is not recommended for use in pregnant women. Flexeril may be excreted in breast milk and should not be used by breastfeeding women.

What else should I know about Flexeril?

It is available as a generic drug and as the brand-name drugs Cymbalta, Irenka, Savella, and Xanax. Flexeril is used to treat spasticity associated with conditions such as multiple sclerosis, ALS, spinal cord injury, and cerebral palsy.

Interactions

Flexeril can interact with other medications, vitamins, or herbs you may be taking. An interaction is when a substance changes the way a drug works. This can be harmful or prevent the drug from working well.

To help avoid interactions, your doctor should manage all of your medications carefully. Be sure to tell your doctor about all medications, vitamins, or herbs you’re taking. To find out how this drug might interact with something else you’re taking, talk to your doctor or pharmacist.

Examples of drugs that can cause interactions with Flexeril are listed below.

Interaction examples

Flexeril and alcohol

Drinking alcohol while taking Flexeril can increase the effects of Flexeril and lead to increased drowsiness and dizziness.

Flexeril and other drugs that make you sleepy

Taking Flexeril with other drugs that make you sleepy can increase the effects of Flexeril and lead to increased drowsiness. Examples of these drugs include:

barbiturates such as phenobarbital

benzodiazepines such as alprazolam, diazepam, and lorazepam

opioids such as codeine, hydrocodone, and oxycodone

tricyclic antidepressants such as amitriptyline and nortriptyline

zolpidem

Flexeril and MAO inhibitors

MAO inhibitors (MAOIs) are a class of drugs used to treat depression. Taking Flexeril with MAOIs can cause dangerous or life-threatening side effects. Examples of MAOIs include:

isocarboxazid

linezolid

methylene blue

phenelzine

tranylcypromine

selegiline

Flexeril and SSRIs

SSRIs are a class of drugs used to treat depression. Taking Flexeril with SSRIs can cause dangerous or life-threatening side effects. Examples of SSRIs include:

citalopram

escitalopram

fluoxetine

paroxetine

sertraline

Flexeril and warfarin

Taking Flexeril with warfarin can increase the effects of warfarin and lead to increased bleeding.