Zofran is a medication used to prevent nausea and vomiting. It is typically used in cancer patients undergoing chemotherapy. Zofran may also be used for other purposes not listed in this medication guide.

Side Effects:

Zofran may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:



-dry mouth or throat


Zofran may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.


Zofran is available in the following doses:

4 mg disintegrating tablets

8 mg orally disintegrating tablets

16 mg/24 hours orally disintegrating tablets

Zofran may be taken with or without food. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take Zofran exactly as directed.

Do not take more or less of it or take it more often than prescribed by your doctor.

If you take Zofran for nausea and vomiting caused by chemotherapy, you will probably take it on the day of your chemo treatment and for the next few days afterward.


Zofran may cause drowsiness or dizziness. These effects may be worse if you take it with alcohol or certain medicines. Use Zofran with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.