What is Clinoril?
Clinoril is a nonsteroidal anti-inflammatory drug (NSAID) used to relieve pain, tenderness, swelling, and stiffness caused by osteoarthritis (arthritis caused by a breakdown of the lining of the joints), rheumatoid arthritis (arthritis caused by swelling of the lining of the joints), juvenile arthritis (a type of arthritis that affects children), and ankylosing spondylitis (arthritis that mainly affects the spine). Clinoril is also used to relieve other types of pain, including menstrual cramps. Clinoril is in a class of medications called NSAIDs. It works by stopping the body’s production of a substance that causes pain and inflammation.
How should Clinoril be used?
Clinoril is available as a tablet and an oral suspension (liquid). Clinoril is usually taken four times a day with food. To reduce your risk of stomach bleeding and other side effects, take Clinoril at the lowest effective dose for the shortest possible time. Do not take more of it, do not take it more often, and do not take it for a longer time than recommended by your doctor.
Shake the liquid form of Clinoril well before each use to mix the medication evenly.
Do not take Clinoril if you have had an asthma attack, hives, or other allergic
Commonly reported side effects of Clinoril include:
Other side effects include:
dry mouth, and
Clinoril can cause serious side effects in some people. If you experience any of these serious side effects while taking Clinoril, stop taking Clinoril immediately and call your doctor:
black stools or vomit that looks like coffee grounds (signs of internal bleeding), severe stomach pain or cramping blue skin discoloration confusion fainting fast breathing or heartbeat hives, itching, or skin rash inability to move arms or legs low blood pressure (feeling dizzy or lightheaded when standing up) ringing in the ears swelling of the face, throat, tongue, lips, eyes, hands, feet, ankles, lower legs or sex organs unusual bruising or bleeding (nosebleeds, bleeding gums) vision changes
Clinoril can also cause less serious side effects. Continue taking Clinoril and talk to your doctor if you experience:
mild diarrhea headache mild dizziness mild stomach pain stuffy nose
Mechanism of Action:
Clinoril’s exact mechanism of action is unknown. However, it is thought to work by inhibiting the synthesis of prostaglandins, which are chemicals that play a role in pain and inflammation.
The recommended dosage of Clinoril for adults is 200-400 mg daily, taken in divided doses. The maximum recommended dosage is 3200 mg daily. For children, the dosage is based on weight.
Clinoril should be taken with food to reduce the risk of stomach upset. Clinoril should be taken at the same time each day to maintain an even level of medication in your blood.
If you miss a dose of Clinoril, take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take two doses of Clinoril at the same time.
Alternatives to Clinoril
NSAIDs such as ibuprofen, naproxen, and celecoxib. Clinoril may not be suitable for people with heart disease, high blood pressure, kidney disease, or liver disease. Clinoril may also not be suitable for people who are taking certain medications such as blood thinners or steroids. Talk to your doctor about all of your options before deciding on a treatment plan.
Clinoril is also sometimes used to treat gout and pain from surgery or joint injury. Clinoril should not be used for pain that is not caused by inflammation. Clinoril is not a narcotic pain reliever and should not be used to treat pain that is not caused by inflammation. Clinoril should not be used in children under the age of 18 unless directed by a doctor. Clinoril should not be taken during pregnancy unless directed by a doctor. Clinoril may pass into breast milk and could harm a nursing baby. Talk to your doctor before taking Clinoril if you are breastfeeding.
Clinoril can increase the risk of serious and potentially fatal side effects such as heart attack, stroke, and internal bleeding. Clinoril should not be used by people with heart disease, high blood pressure, or a history of stroke or blood clotting disorders. Clinoril should also not be used by people who are taking blood thinners or steroids. Clinoril can also increase the risk of stomach and intestinal ulcers and bleeding. Clinoril should be used with caution in people with a history of ulcers or gastrointestinal bleeding. Clinoril should not be taken for longer than recommended by your doctor. Clinoril can cause serious kidney problems. Clinoril should be used with caution in people with kidney disease or a history of kidney problems. Clinoril should not be taken during pregnancy unless directed.