Trade name

Alinia is marketed by Pfizer under the trade name Alinia.

Generic name: rilpivirine.

Brand names: Alinia, Edurant

Alinia (aliniamide) is a medication used to treat infections caused by certain types of bacteria. It belongs to a class of drugs known as aminoglycosides. Alinia works by killing bacteria or preventing their growth.

Alinia is available as an oral suspension and as a tablet. It is usually taken three times daily, with or without food.

Common side effects of Alinia include upset stomach, diarrhea, and dizziness. This medication can also cause kidney damage, so it is important to drink plenty of fluids while taking it.

Alinia is a prescription medication that should be used only as directed by your healthcare provider. It is important to finish the entire course of treatment even if you are feeling better. If you stop taking Alinia too soon, the infection may not be completely cured and could come back.



Alinia is rapidly absorbed from the gastrointestinal tract and achieves peak concentrations in 1-2 hours. It is widely distributed throughout the body, with levels in cerebrospinal fluid exceeding those in serum. Alinia crosses the placenta and is distributed into breast milk. The half-life of alinia is 2-3 hours.


Alinia is indicated for the treatment of infections caused by susceptible strains of bacteria including:

  • Pseudomonas aeruginosa
  • Escherichia coli
  • Klebsiella pneumoniae
  • Enterobacter cloacae
  • Shigella flexneri
  • Serratia marcescens

Alinia may also be used for purposes not listed in this medication guide.

Side Effects

Common side effects of Alinia include:

  • nausea
  • vomiting
  • diarrhea
  • dizziness
  • headache
  • upset stomach or abdominal pain
  • rash or itching

Alinia may also cause kidney damage. Drink plenty of fluids while taking this medication to lower your risk of kidney stones forming. Report any unusual urinary symptoms (pain, blood in the urine) to your doctor. Call your doctor if you have any other problems while taking this medication.

Serious side effects of Alinia include:

  • hearing loss or ringing in the ears
  • kidney damage
  • seizures
  • drowsiness or tiredness
  • difficulty breathing or swallowing
  • confusion or agitation
  • muscle weakness or paralysis

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Dosage and Administration

Alinia is available as an oral suspension and tablets.

The recommended dose of Alinia for adults is 500 mg every 8 hours. For children weighing less than 40 kg, the recommended dose is 15 mg/kg every 8 hours.

Alinia should be taken with food or milk to minimize gastrointestinal side effects.

To ensure that the correct dose is given, measure the suspension carefully with a dosing syringe, calibrated measuring spoon, or graduated cup. Shake the suspension well before each use.

The tablet may be swallowed whole or crushed and mixed with food or liquid.

If you miss a dose of Alinia, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at the next regularly scheduled time. Do not take two doses of Alinia at the same time.


If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 999. Otherwise, call a poison control center right away.


Alinia should be stored at room temperature, 15 C to 30 C (59 F to 86 F). Protect from light and moisture. Do not store in the bathroom. Keep Alinia out of the reach of children and away from pets.