What is Aldactazide?

Aldactazide is a medication that contains a combination of two drugs: spironolactone and hydrochlorothiazide. It’s used to treat high blood pressure and fluid retention (edema).

How does Aldactazide work?

Aldactazide works by helping the body get rid of excess water and salt. It does this by increasing urine output and decreasing the amount of salt absorbed by the body.

What are the benefits of Aldactazide?

Aldactazide can help to lower blood pressure and reduce fluid retention. This can help to improve symptoms such as shortness of breath and swelling in the legs and feet.

What are the risks of Aldactazide?

Aldactazide can cause side effects such as dizziness, headache, and diarrhea. It can also cause potassium levels in the blood to become too high. This can be dangerous for people with kidney problems or heart conditions.

Aldactazide is a prescription medication. It’s available as a tablet and an oral solution. Aldactazide is not available as a generic drug.

Dosages of Aldactazide:

-Tablets: 25 mg/15 mg, 50 mg/25 mg

-Oral solution: 10 mg/5 mg per 5 mL

Strengths of Aldactazide:

-25 mg/15 mg

-50 mg/25 mg

Formulations of Aldactazide:

-Oral solution

-Tablet

Aldactazide is a prescription medication. It’s available as a tablet and an oral solution. Aldactazide is not available as a generic drug.

Pharmacokinetics of Aldactazide:

-Bioavailability: 75%

-Protein binding: 94-98%

-Metabolism: Hepatic (CYP3A4)

-Half-life: 1.4 hours

The Aldactazide oral solution and tablet are bioequivalent. This means that they are equally absorbed into the body.

Aldactazide is a prescription medication. It’s available as a tablet and an oral solution. Aldactazide is not available as a generic drug.

Aldactazide Warnings:

Aldactazide contains a black box warning because it can cause serious side effects. These side effects include low blood potassium levels and high blood calcium levels. Aldactazide can also cause birth defects.

Aldactazide should not be used during pregnancy unless the benefits outweigh the risks. If you become pregnant while taking Aldactazide, stop taking the medication and call your doctor right away.

Aldactazide can pass into breast milk and may harm a nursing baby. You should not breastfeed while taking Aldactazide.

Aldactazide Interactions:

Aldactazide can interact with other medications, vitamins, or herbs you may be taking. An interaction is when a substance changes the way a drug works. This can be harmful or prevent the drug from working well.

To help avoid interactions, your doctor should manage all of your medications carefully. Be sure to tell your doctor about all medications, vitamins, or herbs you’re taking. To find out how this drug might interact with something else you’re taking, talk to your doctor or pharmacist.

Examples of drugs that can cause interactions with Aldactazide are listed below.

-Diuretics

-Potassium-sparing diuretics

-Potassium supplements

-ACE inhibitors

-Angiotensin II receptor blockers (ARBs)

-Nonsteroidal anti-inflammatory drugs (NSAIDs)

If you have questions about drug interactions that may affect you, ask your doctor or pharmacist.

Aldactazide and Alcohol:

You should avoid drinking alcohol while taking Aldactazide. Drinking alcohol can increase your risk of low blood potassium levels.

Overdosages of Aldactazide:

An overdose of Aldactazide can be dangerous.

Overdose symptoms may include the following:

-Dizziness

-Diarrhea

-Headache

-Increased urination

-Low blood pressure

-Muscle weakness

Mechanism of Action of Aldactazide:

Aldactazide is a diuretic. It works by increasing the amount of salt and water that’s eliminated from the body. This helps to lower blood pressure and reduce fluid retention.

How to Take Aldactazide:

-Take Aldactazide exactly as prescribed by your doctor.

-Aldactazide is usually taken once or twice a day.

-You can take Aldactazide with or without food.

-Shake the oral suspension well before each use.

-Measure the oral suspension with a marked measuring spoon, oral syringe, or medicine cup.

-The tablet may be crushed and mixed with water if you have trouble swallowing it whole.

-To prevent dehydration, drink plenty of fluids unless your doctor tells you otherwise.

Aldactazide is usually taken for 4 weeks or less. Your blood pressure will need to be checked often during treatment. You may need to take Aldactazide for a longer time if your blood pressure does not stay down.

If you stop taking Aldactazide suddenly, your blood pressure may increase.