Generic Name: Rabeprazole
Brand Names: Aciphex, Pariet
AcipHex is a proton pump inhibitor that reduces stomach acid production. It is used to treat gastroesophageal reflux disease (GERD), ulcers, and other conditions caused by excess stomach acid. AcipHex may also be used for purposes not listed in this medication guide….
Aciphex is a proton pump inhibitor that works by decreasing the amount of acid produced in the stomach. This can help to relieve symptoms of GERD and other conditions caused by excess stomach acid. AcipHex may also be used for other purposes not listed in this medication guide. You should take Aciphex exactly as prescribed by your doctor. Do not take it in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label. Take each dose with a full glass of water. Aciphex can be taken with or without food. Call your doctor if you have trouble swallowing the tablet whole. To make sure Aciphex is safe for you, tell your doctor if you have ever had: kidney disease; liver disease; or low levels of magnesium in your blood. FDA pregnancy category B. Aciphex is not expected to be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment with Aciphex. It is not known whether rabeprazole passes into breast milk or if it could harm a nursing baby. You should not breast-feed while using this medicine.
Aciphex is rapidly absorbed following oral administration, with peak plasma concentration occurring within 0.5 to 2 hours after dosing. The mean bioavailability of a 20 mg dose of Aciphex compared to an intravenous dose is approximately 77%. Food does not affect the extent of absorption but delays the time to reach peak concentration by 1 hour. Rabeprazole is more than 99% bound to plasma proteins…Rabeprazole is a white to yellowish-white powder and is insoluble in water. Each delayed-release tablet for oral administration contains 20 mg or 40 mg of rabeprazole sodium, USP equivalent to 16.6 mg or 33.3 mg of rabeprazole, respectively…
ACIPHEX (rabeprazole sodium) delayed-release tablets are available in 20 mg strengths, pale yellow, round, biconvex, film-coated tablets debossed with ’20’ on one side and plain on the other side.40 mg strengths: off-white, pentagon shaped, biconvex, film coated tablets debossed with “40” on one side and plain on the reverse side…
AcipHex may interact with other medications you are taking, including over-the-counter drugs and vitamins. This can lead to potentially dangerous side effects, so be sure to tell your doctor about all the medications you are taking before starting AcipHex. Also, let your doctor know if you are taking any antacids or other proton pump inhibitors. You should not take AcipHex if you are also taking rilpivirine, as this can lead to dangerous side effects. Be sure to tell your doctor about all the medications you are taking before starting treatment with AcipHex.AcipHex may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away: headache; diarrhea; constipation; nausea; vomiting; gas; or dry mouth. If you experience any of the following symptoms, call your doctor immediately: rash; hives; itching; difficulty breathing or swallowing; swelling of the face, throat, tongue, lips, eyes, hands, feet, ankles, or lower legs; hoarseness; or unusual bruising or bleeding. AcipHex may cause other side effects. Call your doctor if you have any unusual problems while taking this medication. If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration’s (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch)
You should not use this medicine if you are allergic to rabeprazole or similar medicines such as lansoprazole (Prevacid), omeprazole (Prilosec, Zegerid), pantoprazole (Protonix), or esomeprazole (Nexium). To make sure rabeprazole is safe for you, tell your doctor if you have ever had: kidney disease; liver disease; or low levels of magnesium in your blood. FDA pregnancy category B. Rabeprazole is not expected to be harmful to an unborn baby.
Aciphex is available in tablet form and is usually taken once daily, with or without food. You should take Aciphex exactly as prescribed by your doctor. Do not take it in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label. Aciphex can be taken with or without food. Call your doctor if you have trouble swallowing the tablet whole.
If you take too much Aciphex, call your doctor or go to the nearest hospital emergency room right away. Symptoms of an Aciphex overdose may include: confusion; drowsiness; headache; fast heartbeat; sweating; flushing (warmth, redness, or tingly feeling); seizures.
If you miss a dose of Aciphex, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.
Store this medication at room temperature away from moisture and heat. Keep the bottle tightly closed when not in use.